25947-69-7

Upstream product

• 120-80-9 benzene-1,2-diol 
• 7051-34-5 cyclopropylcarbinyl bromide 
• 5911-08-0 chloro(cyclopropyl)methane 

Downstream Products

• 680184-56-9 4-bromo-2-cyclopropylmethoxyphenol 
• 28584-04-5 Diaethyl-<(4-cyclopropylmethoxy-3-tetradecyloxyanilino)-methylen>malonat 
• 28583-94-0 2-[(4-Cyclopropylmethoxy-3-propoxy-phenylamino)-methylene]-malonic acid diethyl ester 
• 28584-01-2 3-n-Decyloxy-4-cyclopropylmethoxy-anilinomethylen-malonsaeurediethylester 
• 25934-33-2 2-Cyclopropylmethoxy-5-nitrophenyl-tetradecylether 
• 28583-98-4 2-Benzyloxy-1-cyclopropylmethoxy-4-nitro-benzene 
• 21315-15-1 o-Cyclopropylmethoxyphenyl-benzoat 

Relevant academic research and scientific papers

Trifluoromethyl Nonaflate: A Practical Trifluoromethoxylating Reagent and its Application to the Regio- and Stereoselective Synthesis of Trifluoromethoxylated Alkenes

The trifluoromethoxy group has elicited much interest among drug and agrochemical discovery teams because of its unique properties. We developed trifluoromethyl nonafluorobutanesulfonate (nonaflate), TFNf, an easy-to-handle, bench-stable, reactive, and scalable trifluoromethoxylating reagent. TFNf is easily and safely prepared in a simple process in large scale and the nonaflyl part of TFNf can easily be recovered as nonaflyl fluoride after usage and recycled. The synthetic potency of TFNf was showcased with the underexplored synthesis of various trifluoromethoxylated alkenes, through a high regio- and stereoselective hydro(halo)trifluoromethoxylation of alkyne derivatives such as haloalkynes, alkynyl esters, and alkynyl sulfones. The synthetic merits of TFNf were further underscored with a high-yielding and smooth nucleophilic trifluoromethoxylation of alkyl triflates/bromides and primary/secondary alcohols.

PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS

The present invention relates to picolinic acid derivatives that are useful in treating fungal diseases, particularly fungal diseases of agricultural crop plants.

PROCESS FOR PRODUCTION OF FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR INTERMEDIATES

Roflumilast and new key intermediates therefor are prepared by processes involving use of carbonylation technology. Good overall yields can be achieved using available starting materials. The starting material for the process can be catechol, an o-R1

ANTIHYPERTENSIVE 3-(UREIDOCYCLOHEXYLENEAMINO)PROPANE-1,2-DIOL DERIVATIVES

Certain 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives, such as the compounds of formula III below, represent novel and useful pharmaceutical agents, e.g. potent antihypertensive and cardioactive agents demonstrating both α-and β-adrenergic bloc