259541-89-4

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 4334-88-7 p-ethoxycarbonylphenylboronic acid 
• 5798-75-4 Ethyl 4-bromobenzoate 

Downstream Products

• 1200123-95-0 ethyl 3-chloro-4-(pyrimidin-2-yl)benzoate 
• 1217189-17-7 ethyl 3,5-dichloro-4-(pyrimidin-2-yl)benzoate 
• 1217189-18-8 ethyl 3,5-dibromo-4-(pyrimidin-2-yl)benzoate 
• 1446325-97-8 C₂₁H₁₅N₃O₄ 
• 1446325-98-9 C₂₉H₁₈N₄O₆ 
• 1436430-39-5 tetraethyl 2,2′-(5-(ethoxycarbonyl)-2-(pyrimidin-2-yl)-1,3-phenylene)dimalonate 

Relevant academic research and scientific papers

Cobalt-Catalyzed Preparation of N -Heterocyclic Organozinc Reagents from the Corresponding Heteroaryl Chlorides

Various substituted and unsubstituted N -heteroaryl chlorides have been converted into their corresponding organozinc species using zinc dust in the presence of zinc pivalate and 10% CoCl 2in benzonitrile at 25 °C. The resulting heteroarylzinc

Palladium-Catalyzed Regioselective C-H Bond ortho-Acetoxylation of Arylpyrimidines

An efficient and regioselective palladium-catalyzed ortho C-H acetoxylation reaction was developed to afford, ortho monoacetoxylated arylpyrimidmes in good to excellent yields by using cupric trifluoroacetate as a cocatalyst. A wide variety of oxygenated

Palladium-catalyzed monoselective halogenation of C-H bonds: Efficient access to halogenated arylpyrimidines using calcium halides

A wide variety of ortho-halogenated arylpyrimidines were prepared with high monoselectivity and functional-group tolerance by using calcium halides as crucial halogenating agents and cupric trifluoroacetate as oxidant in the presence of air.

Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic organozinc reagents and their coupling with 2-chlorodia

Electrochemical cross-coupling between functionalized aryl halides and 2-chloropyrimidine or 2-chloropyrazine catalyzed by nickel 2,2'-bipyridine complex

2-Arylpyrimidines and 2-arylpyrazines have been obtained in good to high yields from 2-chloropyrimidine and 2-chloropyrazine and various functionalized aryl halides by electroreduction using an iron rod as the anode and a catalytic amount of nickel-bipyridine complex in a mixture of DMF and pyridine as solvent.