259655-01-1 Usage
General Description
6,8-Difluorochroman-4-one is a chemical compound with the molecular formula C9H5F2O2. It belongs to the class of organic compounds known as chromanones. 6,8-Difluorochroman-4-one is a derivative of chromanone and possesses two fluorine atoms at positions 6 and 8. 6,8-Difluorochroman-4-one has potential applications in the synthesis of pharmaceuticals and as a building block in organic chemical reactions. The compound may also have interesting biological and pharmacological activities which could make it a subject of interest for further research. Its unique structure and properties make it an important target for chemical studies and potential industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 259655-01-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,6,5 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 259655-01:
(8*2)+(7*5)+(6*9)+(5*6)+(4*5)+(3*5)+(2*0)+(1*1)=171
171 % 10 = 1
So 259655-01-1 is a valid CAS Registry Number.
259655-01-1Relevant articles and documents
Synthesis, determination of absolute configuration, and biological evaluation of spiro-fused thiadiazoline inhibitors of kinesin spindle protein (KSP)
Angeles, Angie R.,Yang, Liping,Dai, Chaoyang,Brunskill, Andrew,Basso, Andrea D.,Siddiqui, M. Arshad
supporting information; experimental part, p. 6236 - 6239 (2011/01/12)
A facile and highly convergent synthesis of biologically active spiro-fused thiadiazoline KSP inhibitors is reported. The highlights of the synthesis include the Michael reaction and cyclization of thiosemicarbazone to 1,3,4-thiadiazoline. This chemistry lends itself to the preparation of (+)-2, a potent and orally bioavailable anti-cancer agent, and to the development of a structure-activity relationship program.
