259667-43-1

Basic information

• Product Name: 5-Bromo-6-chloro-1H-indole-2,3-dione
• Synonyms: 5-Bromo-6-chloro-1H-indole-2,3-dione
• CAS NO: 259667-43-1
• Molecular Formula: C₈H₃BrClNO₂
• Molecular Weight: 260.48
• Mol File: 259667-43-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.919±0.06 g/cm3(Predicted)
• PKA: 7.72±0.20(Predicted)
• CAS DataBase Reference: 5-Bromo-6-chloro-1H-indole-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-6-chloro-1H-indole-2,3-dione(259667-43-1)
• EPA Substance Registry System: 5-Bromo-6-chloro-1H-indole-2,3-dione(259667-43-1)

Safety Data

• Hazardous Substances Data: 259667-43-1(Hazardous Substances Data)

Upstream product

• 6341-92-0 6-chloroisatin 

Downstream Products

• 1195960-93-0 2-(4-(5-bromo-6-chloro-2-oxoindolin-3-ylidene)-5-oxo-2-thioxoimidazolidin-1-yl)-3-phenylpropanoic acid 

Relevant articles and documents

Compound with AMPK agonistic activity and preparation and application of prodrug thereof

The invention relates to a compound with AMPK agonistic activity and a prodrug thereof, and as well as a preparation method and medical application of a prodrug thereof. The compound has the structure shown in the formula (I), and the prodrug of the compound has the structure shown in the formula (II), wherein each group and the substituent are as defined in the specification. The invention discloses a preparation method of the compound and application of the compound in prevention and treatment AMPK related diseases, and the AMPK related diseases include, but are not limited to, energy metabolism abnormality related diseases. Neurodegenerative diseases and inflammation-related diseases and the like.