259742-00-2

Upstream product

• 85-44-9 phthalic anhydride 
• 210833-99-1 phenyl 2,3,4-tri-O-benzyl-1-thio-D-glucopyranoside 

Downstream Products

• 259742-10-4 Phthalic acid 1-[(2R,3R,4S,5R,6S)-4,5-bis-benzyloxy-6-methoxy-3-(2,2,2-trichloro-ethoxycarbonyloxy)-tetrahydro-pyran-2-ylmethyl] ester 2-((2R,3R,4S,5R)-3,4,5-tris-benzyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl) ester 
• 259742-04-6 Phthalic acid 1-((2R,3R,4S,5R,6S)-4,5-bis-benzyloxy-3-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl) ester 2-((2R,3R,4S,5R)-3,4,5-tris-benzyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl) ester 

Relevant academic research and scientific papers

Novel molecular clamp method for anomeric stereocontrol of glycosylation

Stereocontrolled glycosylation is described by using a molecular clamp, which binds a glycosyl donor to an acceptor and controls their spatial arrangement. An α(1→4) glycosidic linkage was formed in a good yield with high selectivity by the use of a phthaloyl bridge bound to both 6-positions of a glycosyl donor and an acceptor. β-Selective glycosylation was effected by the use of a silyl bridge attached to the same 6-positions of the same glycosyl donor and acceptor. Application of this method to the synthesis of a maltotetraose derivative is also described.