259868-84-3Relevant academic research and scientific papers
New highly potent GABA uptake inhibitors selective for GAT-1 and GAT-3 derived from (R)- and (S)-proline and homologous pyrrolidine-2-alkanoic acids
Fuelep, Guenther H.,Hoesl, Cornelia E.,Hoefner, Georg,Wanner, Klaus T.
, p. 809 - 824 (2007/10/03)
We synthesized proline and pyrrolidine-2-alkanoic acid derivatives in their enantiomerically pure form and evaluated them for their affinity to the GABA transport proteins GAT-1 and GAT-3. Among the compounds presented herein, (R)-pyrrolidine-2-acetic aci
