260362-01-4Relevant academic research and scientific papers
D-ring substituted rhazinilam analogues: Semisynthesis and evaluation of antitubulin activity
Dupont, Christophe,Guenard, Daniel,Tchertanov, Luba,Thoret, Sylviane,Gueritte, Francoise
, p. 2961 - 2969 (1999)
Novel (-)- and (+)-rhazinilam derivatives substituted on the D-ring (compounds 3, 4, 5 and 6) have been prepared from (+)-vincadifformine 7 and (-)-tabersonine and evaluated against the disassembly of microtubules into tubulin. Along with this study, a re
