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5-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3-OXAPENTANOIC ACID, also known as Fmoc-NH-PEG1-CH2COOH, is a degradable ADC linker used in the synthesis of antibody drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be utilized for the synthesis of proteolysis-targeting chimeras (PROTACs). Fmoc-NH-PEG1-CH2COOH is a solid in appearance and plays a crucial role in the development of various pharmaceutical applications.

260367-12-2

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260367-12-2 Usage

Uses

Used in Pharmaceutical Industry:
5-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3-OXAPENTANOIC ACID is used as a degradable ADC linker for the synthesis of antibody drug conjugates (ADCs). It serves as a crucial component in the development of targeted cancer therapies, enhancing the specificity and efficacy of these treatments.
Additionally, Fmoc-NH-PEG1-CH2COOH is used as a PEG-based PROTAC linker for the synthesis of proteolysis-targeting chimeras (PROTACs). This application is significant in the field of drug discovery, as it allows for the development of novel therapies that can modulate protein degradation pathways, potentially leading to the treatment of various diseases.
Furthermore, 5-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3-OXAPENTANOIC ACID can be used as a reactant or reagent in a modular platform to develop peptoid-based selective fluorescent metal sensors. This application is particularly relevant in the field of analytical chemistry and materials science, where the development of sensitive and selective sensors is of great importance for various research and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 260367-12-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,0,3,6 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 260367-12:
(8*2)+(7*6)+(6*0)+(5*3)+(4*6)+(3*7)+(2*1)+(1*2)=122
122 % 10 = 2
So 260367-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H19NO5/c21-18(22)12-24-10-9-20-19(23)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,20,23)(H,21,22)

260367-12-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]acetic acid

1.2 Other means of identification

Product number -
Other names Fmoc-O1Pen-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:260367-12-2 SDS

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