260391-27-3

Upstream product

• 260391-22-8 (2S)-2-(tert-butoxycarbonylamino)-3-(tert-butyldiphenylsilyloxy)propyl methanesulfonate 
• 260391-23-9 tert-butyl [(R)-1-cyanomethyl-2-(tert-butyldiphenylsilyloxy)ethyl]carbamate 
• 260391-24-0 (3R)-amino-4-(tert-butyldiphenylsilyloxy)butyronitrile 
• 13149-00-3 1,2-cis-cyclohexanedicarboxylic anhydride 
• 198417-69-5 tert-butyl [(1R)-2-(tert-butyldiphenylsilyloxy)-1-(hydroxymethyl)-ethyl]carbamate 
• 159846-14-7 methyl (2S)-3-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-[(tert-butoxy)carbonylamino]propanoate 

Downstream Products

• 260391-31-9 tert-butyl {(3R)-4-(tert-butyldiphenylsilyloxy)-3-[(3aR,7aS)-1-thioxooctahydroisoindol-2-yl]butyl}carbamate 
• 260391-29-5 tert-butyl {(3R)-4-(tert-butyldiphenylsilyloxy)-3-[(3aR,7aS)-1-oxooctahydroisoindol-2-yl]butyl}carbamate 

Relevant academic research and scientific papers

(S)-Pyroglutamic acid, (S)-malic acid, and (S)-serine as useful starting materials in the synthesis of enantiopure hydroxyamidines

The synthesis of four enantiopure hydroxyamidines is described. One amidine was obtained from (S)-pyroglutamic acid. Its key step involved the addition of phenylmagnesium bromide to the corresponding ester, affording the tertiary alcohol without detectabl