260402-97-9Relevant articles and documents
GABA-analogous spirocyclic amino acid esters, 5. n-benzyl-7-azaspiro[4.5]decane-l-carboxylates
Bendl, Markus,Eder, Michael,Langhammer, Ingo,Urban, Ernst
, p. 115 - 126 (2007/10/03)
N-Benzyl-7-azaspiro[4.5]decane-1-carboxylates (4a and 4b) were prepared in a seven step synthesis starting from ethyl cyclopentanonecarboxylate (5). Aminolysis of the β-keto ester (5) with benzylamine led to the β-keto amide (9) which gave the a-substitut