260408-00-2Relevant academic research and scientific papers
Diastereoselective reduction of N-phthaloyl α-amino ketones: Synthesis of syn-3-amino-1,2-diol derivatives
Sengupta, Saumitra,Sen Sarma, Debarati
, p. 485 - 487 (2007/10/03)
LiAlH(OBu-t)3 reduction of the chiral-pool derived N-phthaloyl α-amino-α′-acetoxy ketones has led to a facile diastereoselective synthesis of syn-3-amino-1,2-diols (> 75% de).
Synthesis of (2R, 3S)-3-(N,N-dibenzylamino)-1-thiophenylbutan-2-ol
Sengupta, Saumitra,Sarma, Debarati Sen
, p. 641 - 642 (2007/10/03)
Synthesis of 3-mercapto-1,2-amino alcohols via S-H insertion reaction of in enantiopure N,N-dibenzyl-α-aminodiazoketones followed by a syn-selective borohydride reduction is described.
