260414-17-3Relevant academic research and scientific papers
Synthesis of ethoxy-linked pseudo-disaccharides incorporating a crown ether macrocycle and lectin recognition
Dumont-Hornebeck, Beatrice,Joly, Jean-Pierre,Coulon, Joel,Chapleur, Yves
, p. 214 - 227 (1999)
Six ethoxy-linked pseudo-disaccharides incorporating a non-reducing d- galactopyranosyl residue and a glucose bearing an 18-crown-6-ether were synthesized by the trichloracetimidate method. Deprotection left four novel structures from which two were tested against the galactose-specific lectin Kluyveromyces bulgaricus. Their minimum inhibitory concentration (MIC) was in the same order of magnitude as compared to previously prepared oligosaccharides without spacer.
