26055-65-2

Usage

Uses

Used in Pharmaceutical Industry:
Guanidine, N,N'''-1,4-phenylenebis-, dihydrochloride is used as a pharmaceutical intermediate for the synthesis of various pharmaceutical drugs. Its role in drug development is crucial, as it can be transformed into a wide range of medicinal compounds.
Used in Chemical Industry:
Guanidine,N,N'''-1,4-phenylenebis-,dihydrochloride is used as a precursor in the synthesis of organic compounds, which are essential in the production of various chemical products. Its versatility in chemical reactions makes it a valuable asset in the chemical industry.
Used in Polyurethane Foam Production:
Guanidine, N,N'''-1,4-phenylenebis-, dihydrochloride is used as a component in the creation of polyurethane foams. Its presence in the production process contributes to the formation of the foam's structure and properties.
Used in Epoxy Resin Production:
Guanidine,N,N'''-1,4-phenylenebis-,dihydrochloride is also used in the production of epoxy resins, where it plays a role in the formation of the resin's chemical composition. This contributes to the resin's performance in various applications, such as coatings, adhesives, and composite materials.
It is important to handle Guanidine, N,N'''-1,4-phenylenebis-, dihydrochloride with care, as it may be corrosive and harmful if not used properly. Its applications across different industries highlight its significance in the production of a wide range of products.

Upstream product

• 624-18-0 benzene-1,4-diamine hydrochloride 
• 693-13-0 diisopropyl-carbodiimide 
• 420-04-2 CYANAMID 

Relevant academic research and scientific papers

TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION

The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.

Synthesis, characterization and chemistry of the fluoronitramide anion

The fluoronitramide anion, as its potassium, tetraisopropyl p-phenylenediguanidinium, and tetraphenylphosphonium salts, have been synthesized. The latter salt was characterized in detail as it was by far the most stable. The free acid HN(F)(NO2) was found to be unstable, as was the ammonium salt of fiuoronitramide. The fluorine atom was shown to be capable of displacement by nucleophiles. In contrast to dinitramide, which at room temperature is unreactive towards aqueous alkali, fiuoronitramide reacts instantly with aqueous hydroxide. Single crystal X-ray diffraction data show an unusual degree of uncertainty in the position of the fluorine atom in all of the salts that were examined. Georg Thieme Verlag Stuttgart.

Discovery of small molecule CXCR4 antagonists

In light of a proposed molecular mechanism for the C-X-C chemokine receptor type 4 (CXCR4) antagonist 1 (AMD3100), a template with the general structure 2 was designed, and 15 was identified as a lead by means of an affinity binding assay against the liga

CXCR4 ANTAGONISTS FOR THE TREATMENT OF HIV INFECTION

The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor, and in particular to inhibit viral entry of certain viruses. Certain compounds in particular can reduce entry of immunodeficiency virus (HIV) into a cell while not reducing the capacity of stem cells to proliferate, and therefore can be useful for long term treatment regimes. The compounds are useful in particular in the treatment or prevention of HIV infections.