260551-06-2

Upstream product

• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 260551-05-1 2,6-anhydro-3,4,5,7-tetra-O-benzyl-D-glycero-L-gluco-heptitol 
• 140397-44-0 2,6-anhydro-1,3,4,5-tetra-O-benzyl-7,8,9-trideoxy-D-glycero-L-galacto-non-7,8-dienitol 
• 140397-45-1 2,6-anhydro-3,4,5,7-tetra-O-benzyl-7,8,9-trideoxy-D-glycero-L-gluco-heptose 

Relevant academic research and scientific papers

Synthesis of Novel Donor Mimetics of UDP-Gal, UDP-GlcNAc, and UDP-GalNAc as Potential Transferase Inhibitors

For the enzymatic transfer of galactose, N-acetylglucosamine, and N-acetylgalactosamine, UDP-Gal (1), UDP-GlcNAc (2), and UDP-GalNAc (3) are employed, and UDP serves as a feedback inhibitor. In this paper the synthesis of the novel UDP-sugar analogues 4, 5, and 6 as potential transferase inhibitors is described. Compounds 4-6 feature C-glycosidic hydroxymethylene linkages between the sugar and nucleoside moieties in contrast to the anomeric oxygens in the natural derivatives 1-3.