26057-07-8Relevant academic research and scientific papers
Indium(III)-catalyzed coupling between alkynes and aldehydes to α,β-unsaturated ketones
Miura, Katsukiyo,Yamamoto, Kiyomi,Yamanobe, Aya,Ito, Keisuke,Kinoshita, Hidenori,Ichikawa, Junji,Hosomi, Akira
, p. 766 - 767 (2010)
The combined use of a catalytic amount of InX3 (X = OTf and NTf2) and 1-butanol was found to be effective in formal alkynealdehyde metathesis. With this catalytic system, aromatic alkynes reacted with aromatic aldehydes to give chalcones in moderate to good yields. Alkynals were efficiently converted into 5- to 7-membered cyclic compounds by intramolecular alkyne-aldehyde coupling.
