2606-58-8

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(bromomethyl)-4-propoxybenzene is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure allows for the creation of a wide range of medicinal compounds, contributing to the development of novel treatments and therapies.
Used in Agrochemical Production:
In the agrochemical industry, 1-(bromomethyl)-4-propoxybenzene is utilized as a key intermediate in the production of different agrochemicals. Its role in the synthesis process aids in the development of effective pesticides, herbicides, and other agricultural products that enhance crop protection and yield.
Used in Organic Synthesis:
1-(bromomethyl)-4-propoxybenzene is also employed as a versatile building block in organic synthesis, enabling the creation of a diverse array of chemical products. Its bromomethyl and propoxy groups facilitate various chemical reactions, making it a valuable component in the synthesis of specialty chemicals, dyes, and other industrial products.

InChI:InChI=1/C10H13BrO/c1-2-7-12-10-5-3-9(8-11)4-6-10/h3-6H,2,7-8H2,1H3

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 5736-85-6 4-propoxybenzaldehyde 
• 27079-92-1 4-(bromomethyl)phenol 
• 106-94-5 propyl bromide 
• 5349-18-8 4-methylphenol n-propyl ether 
• 90925-43-2 4-n-propyloxybenzyl alcohol 

Downstream Products

• 3243-40-1 3-(4-propoxy-phenyl)-propionic acid 
• 36931-02-9 (E)-1,2-bis(4-propoxyphenyl)ethene 

Relevant academic research and scientific papers

Identification of 6-benzyloxysalicylates as a novel class of inhibitors of 15-lipoxygenase-1

Lipoxygenases metabolize polyunsaturated fatty acids into signalling molecules such as leukotrienes and lipoxins. 15-lipoxygenase-1 (15-LOX-1) is an important mammalian lipoxygenase and plays a crucial regulatory role in several respiratory diseases such as asthma, COPD and chronic bronchitis. Novel potent and selective inhibitors of 15-LOX-1 are required to explore the role of this enzyme in drug discovery. In this study we describe structure activity relationships for 6-benzyloxysalicylates as inhibitors of human 15-LOX-1. Kinetic analysis suggests competitive inhibition and the binding model of these compounds can be rationalized using molecular modelling studies. The most potent derivative 37a shows a Ki value of 1.7 μM. These structure activity relationships provide a basis to design improved inhibitors and to explore 15-LOX-1 as a drug target.

POLYMERIZABLE COMPOUND AND OPTICAL ANISOTROPIC BODY

PROBLEM TO BE SOLVED: To provide a polymerizable compound that prevents the occurrence of crystal deposition or the like when added to a polymerizable composition and has high storage stability. SOLUTION: This invention provides a compound represented by general formula (I), specifically, a compound of the following structure. This invention also provides a composition comprising the compound, a polymer obtained by polymerization of the composition and an optical anisotropic body using the polymer. COPYRIGHT: (C)2015,JPOandINPIT

Alkoxylated p-phenylenevinylene oligomers: Synthesis and spectroscopic and electrochemical properties

Twenty-one n-alkoxy substituted phenylenevinylene oligomers were synthesized, varying in size, number and position of the OR groups. IR,MS and solubility data are presented. NMR measurements provided the molecular structure as well as information about conformations and molecular dynamics. UV and of cyclic voltammetric data give correlations of chemical structure (number and position of OR substituents) with separate HOMO and LUMO energies.