260802-42-4Relevant articles and documents
Synthesis and biological activities of novel trifluoromethylpyridine amide derivatives containing sulfur moieties
Chen, S. H.,Dai, A. L.,Guo, S. X.,He, F.,Wu, J.,Zhang, R. F.
, p. 35658 - 35670 (2020/10/27)
A series of trifluoromethylpyridine amide derivatives containing sulfur moieties (thioether, sulfone and sulfoxide) was designed and synthesized. Their antibacterial activities against Xanthomonas oryzae pv. oryzae (Xoo), Ralstonia solanacearum (R. solana
A new strategy for the synthesis of β-benzylmercaptoethylamine derivatives
Ghosh, Subrata,Tochtrop, Gregory P.
supporting information; experimental part, p. 1723 - 1726 (2009/07/05)
Here, we describe a new experimental approach to the synthesis of the β-benzylmercaptoethylamine functionality, and illustrate its synthetic utility in multi-component reactions. Although prevalent in modern organic synthesis, no general methods have been described for this functionality. Using a carefully developed LiOH-water-ethanol reaction mixture, we were able to produce a diverse collection of β-benzylmercaptoethylamines containing a range of sensitive functional groups in excellent yields. To further illustrate their utility in molecular library synthesis, we also report the use of β-benzylmercaptoethylamines in five different multi-component reactions.
