26088-79-9

Basic information

• Product Name: 2-(4-Acetamidobenzylidene)malononitrile
• Synonyms: RARECHEM AL BX 0078;4’-(2,2-dicyanovinyl)-acetanilid;2-(ACETAMIDOBENZYLIDENE)MALONONITRILE;2-(ACETAMIDOBENZYLIDENE)MALONONITRILE(A);2-(4-ACETAMIDOBENZYLIDENE) MALONONITRILE;ACETAMIDE, N-[4-(2,2-DICYANOETHENYL)PHENYL]-;alpha-Dicyanomethylene-4-acetotoluidide;N-(4-(2,2-Dicyanovinyl)phenyl)acetaMide
• CAS NO: 26088-79-9
• Molecular Formula: C₁₂H₉N₃O
• Molecular Weight: 211.22
• Mol File: 26088-79-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 475.552 °C at 760 mmHg
• Flash Point: 241.406 °C
• Appearance: /
• Density: 1.268 g/cm³
• Vapor Pressure: 3.29E-09mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 2-(4-Acetamidobenzylidene)malononitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Acetamidobenzylidene)malononitrile(26088-79-9)
• EPA Substance Registry System: 2-(4-Acetamidobenzylidene)malononitrile(26088-79-9)

Safety Data

• Hazardous Substances Data: 26088-79-9(Hazardous Substances Data)

Usage

General Description

"2-(4-Acetamidobenzylidene)malononitrile" is a chemical compound that contains a benzylidene group, making it a type of benzylmalononitrile. Its specific structure includes an acetamido group attached to the benzene ring, which is itself linked to a malononitrile moiety through a methylene bridge. 2-(4-Acetamidobenzylidene)malononitrile is primarily used in organic chemistry as a starting material or intermediate in various reactions, owing to its highly reactive nature. Although it hasn't been extensively studied, like other malononitriles, this compound is likely to be hazardous and must be handled with caution.

InChI:InChI=1/C12H9N3O/c1-9(16)15-12-4-2-10(3-5-12)6-11(7-13)8-14/h2-6H,1H3,(H,15,16)

Upstream product

• 122-85-0 para-acetamidobenzaldehyde 
• 109-77-3 malononitrile 
• 17082-32-5 2-(4-aminobenzylidene)malononitrile 
• 108-24-7 acetic anhydride 

Downstream Products

• 1239708-63-4 t-butyl 4-((4-(3-(6-((4-(4-acetamidophenyl)-6-amino-5-cyanopyrimidin-2-ylthio)methyl)-1-oxy-pyridin-2-yl)propanoyl)piperazin-1-yl)methyl)piperidine-1-carboxylate 
• 1239708-57-6 t-butyl 4-((4-(3-(6-((4-amino-6-(4-aminophenyl)-5-cyanopyrimidin-2-ylthio)methyl)pyridin-2-yl)propanoyl)piperazin-1-yl)methyl)piperidine-1-carboxylate 
• 1239708-56-5 3-(6-(4-Amino-6-(4-aminophenyl)-5-cyanopyrimidin-2-ylthio-methyl)pyridin-2-yl)propionic acid 
• 1239708-60-1 N-(4-(6-amino-5-cyano-2-mercaptopyrimidin-4-yl)phenyl)acetamide 

Relevant articles and documents

Pseudo-five-component organocatalyzed synthesis of dicyanoanillines using only malononitrile and aromatic aldehydes

A pseudo-five-component reaction leading to efficient synthesis of dicyanoanillines was developed using only aromatic aldehydes and malononitrile as the starting reactants. Mechanistic studies suggested that a malononitrile dimer and the Knoevenagel conde

The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2B receptor

A new series of amino-3,5-dicyanopyridines (3–28) as analogues of the adenosine hA2B receptor agonist BAY60-6583 (compound 1) was synthesized. All the compounds that interact with the hA2B adenosine receptor display EC50 v

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