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5H-pyrido[3,4-b][1,4]benzothiazine is a heterocyclic compound characterized by a unique structure that fuses a pyridine ring with a benzothiazine ring. This chemical is notable for its potential applications in medicinal chemistry, particularly as a scaffold for the development of new drugs. The compound's structure allows for a range of functional group modifications, which can lead to the creation of diverse derivatives with varying biological activities. Its chemical properties and reactivity are influenced by the presence of both nitrogen and sulfur atoms in the ring system, which can participate in various chemical reactions. The study of 5H-pyrido[3,4-b][1,4]benzothiazine and its derivatives is an active area of research, with the aim of discovering new therapeutic agents that can target specific diseases or conditions.

261-90-5

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261-90-5 Usage

Structure

Fused tricyclic structure containing a pyridine ring condensed with a benzothiazine ring

Classification

Heterocyclic compound

Derivative of

Benzothiazine

Definition

Organic compound with a benzene ring fused to a thiazine ring

Potential Applications

Pharmaceutical applications due to its structural features and potential biological activities

Significance

Worth studying for potential use in drug discovery and development

Check Digit Verification of cas no

The CAS Registry Mumber 261-90-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 261-90:
(5*2)+(4*6)+(3*1)+(2*9)+(1*0)=55
55 % 10 = 5
So 261-90-5 is a valid CAS Registry Number.

261-90-5Relevant academic research and scientific papers

AZAPHENOTHIAZINES AND AZAPHENOXAZINES AS ANTIOXIDANTS

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Paragraph 00125, (2018/10/24)

The present disclosure relates generally to antioxidants. More particularly, the present disclosure relates to lubricating compositions comprising an antioxidant.

Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors

Madrid, Peter B.,Polgar, Willma E.,Toll, Lawrence,Tanga, Mary J.

, p. 3014 - 3017 (2008/02/07)

Analogs of the psychotropic phenothiazines were synthesized and examined as antitubercular agents against Mycobacterium tuberculosis H37Rv. The compounds were subsequently counter-screened for binding to the dopaminergic-receptor subtypes D1, D2, D3 and the serotonergic-receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2C. The most active compounds showed MICs from 2 to 4 μg/mL and had overall reduced binding to the dopamine and serotonin receptors compared to chlorpromazine and trifluoperazine.

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