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Actinomycin VI is a naturally occurring, cytotoxic antibiotic belonging to the actinomycin family, which is produced by certain Streptomyces bacteria. It is known for its antitumor properties and is used in the treatment of various types of cancer, including Wilms' tumor and neuroblastoma. Actinomycin VI works by intercalating into DNA, inhibiting both DNA replication and transcription, which ultimately leads to the suppression of cell division and the induction of apoptosis in cancer cells. Due to its potent effects and potential side effects, its use is often limited to specific cancer types and is administered under strict medical supervision.

2612-14-8

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Basic information
1. Product Name: Actinomycin VI
2. Synonyms: Actinomycin VI;2-amino-1-N-(3-butan-2-yl-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-10-propan-2-yl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl)-4,6-dimethyl-3-oxo-9-N-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide;2-amino-N'-(3,10-diisopropyl-2,5,9,12,15-pentaketo-7,11,14-trimethyl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl)-N-(10-isopropyl-2,5,9,12,15-pentaketo-7,11,14-trimethyl-3-sec-butyl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl)-3-keto-4,6-dimethyl-phenoxazine-1,9-dicarboxamide;2-azanyl-N1-(3-butan-2-yl-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-10-propan-2-yl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl)-4,6-dimethyl-3-oxo-N9-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
3. CAS NO:2612-14-8
4. Molecular Formula: C63H88N12O16
5. Molecular Weight: 1269.46
6. EINECS: 232-485-1
7. Product Categories: N/A
8. Mol File: 2612-14-8.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 1388.3°Cat760mmHg
3. Flash Point: 793.4°C
4. Appearance: /
5. Density: 1.41g/cm³
6. Vapor Pressure: 0mmHg at 25°C
7. Refractive Index: 1.653
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: Actinomycin VI(CAS DataBase Reference)
11. NIST Chemistry Reference: Actinomycin VI(2612-14-8)
12. EPA Substance Registry System: Actinomycin VI(2612-14-8)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. RIDADR: 3249
5. WGK Germany:
6. RTECS:
7. HazardClass: 6.1(a)
8. PackingGroup: II
9. Hazardous Substances Data: 2612-14-8(Hazardous Substances Data)

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2612-14-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2612-14-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,1 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2612-14:
(6*2)+(5*6)+(4*1)+(3*2)+(2*1)+(1*4)=58
58 % 10 = 8
So 2612-14-8 is a valid CAS Registry Number.

InChI:InChI=1/C63H88N12O16/c1-17-31(8)44-61(86)75-25-19-21-38(75)59(84)71(14)27-40(77)73(16)50(30(6)7)63(88)90-35(12)46(57(82)67-44)69-55(80)41-42(64)51(78)33(10)53-48(41)65-47-36(23-22-32(9)52(47)91-53)54(79)68-45-34(11)89-62(87)49(29(4)5)72(15)39(76)26-70(13)58(83)37-20-18-24-74(37)60(85)43(28(2)3)66-56(45)81/h22-23,28-31,34-35,37-38,43-46,49-50H,17-21,24-27,64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)/t31-,34+,35+,37-,38-,43+,44+,45-,46-,49-,50-/m0/s1

2612-14-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	Actinomycin VI

1.2 Other means of identification

Product number	-
Other names	actinomycin C2

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2612-14-8 SDS

2612-14-8Upstream product

28607-40-1 (A2-D-alloisoleucine)-actinomycin-A5-oic-D acid

2612-14-8Downstream Products

2612-14-8Relevant academic research and scientific papers

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