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7H-Pyrido[2,1-b]quinazoline, 6,8,9,11-tetrahydro- is a complex organic compound belonging to the pyridoquinazoline family. It is characterized by a fused pyridine and quinazoline ring system, with four hydrogen atoms attached to the 6, 8, 9, and 11 positions, resulting in a tetrahydro derivative. 7H-Pyrido[2,1-b]quinazoline, 6,8,9,11-tetrahydro- is of interest in medicinal chemistry due to its potential biological activities and its structural similarity to certain alkaloids found in nature. The specific properties and applications of 7H-Pyrido[2,1-b]quinazoline, 6,8,9,11-tetrahydro- may vary depending on its functional groups and substituents, which can influence its reactivity and interactions with biological targets.

2614-49-5

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2614-49-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2614-49-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,1 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2614-49:
(6*2)+(5*6)+(4*1)+(3*4)+(2*4)+(1*9)=75
75 % 10 = 5
So 2614-49-5 is a valid CAS Registry Number.

2614-49-5Relevant academic research and scientific papers

Acetylcholinesterase inhibition by fused dihydroquinazoline compounds

Jaen, Juan C.,Gregor, Vlad E.,Lee, Chet,Davis, Robert,Emmerling, Mark

, p. 737 - 742 (2007/10/03)

A new type of dihydroquinazoline-based inibitor of acetylcholinesterase (AChE) is described. These compounds were designed to interact with the catalytic site of AChE in a manner similar to the known inhibitor tacrine. In a manner analogous to the potency enhancement obtained by addition of chlorine atoms to the tacrine molecule, a 3-chloro derivative of the parent hexahydroazepino[2,1-b]quinazoline structure was found to be about 8 times more potent as an AChE inhibitor than the unsubstituted compound.

Studies on Some Biologically Active Azepinoquinazolines: Part I - An Approach to Potent Bronchodilatory Compounds

Malhotra, S.,Koul, S. K.,Sharma, R. L.,Anand, K. K.,Gupta, O. P.,Dhar, K. L.

, p. 937 - 940 (2007/10/02)

Twenty six azepinoquinazolines have been prepared and screened for their bronchodilatory activity.Out of these compounds, 7,8,9,10-tetrahydroazepinoquinazolin-12(6H)-one (III) has been found as an excellent bronchodilatory compound. 2,4,6-Tribromo-7,8,9,10-tetrahydroazepinoquinazolin-12(6H)-one (XXIV) shows marked antitussive and mucolytic activities parallel to those of bromhexine.

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