26145-14-2

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC& is used as a key intermediate in the development of new drugs and pharmaceuticals. Its unique chemical structure allows for the creation of a wide range of therapeutic agents with potential applications in various medical fields.
Used in Organic Synthesis:
As a building block in organic synthesis, 4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC& is utilized for the preparation of various organic compounds. Its reactive nature enables the formation of diverse molecular structures, contributing to the advancement of organic chemistry.
Used in Research and Chemical Processes:
4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC& is also employed in various research and chemical processes due to its unique chemical properties. Its potential applications in these areas further highlight the significance of 4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC& in the field of chemistry.

InChI:InChI=1/C11H7BrO2S/c12-9-3-1-7(2-4-9)8-5-10(11(13)14)15-6-8/h1-6H,(H,13,14)

Downstream Products

• 1394169-59-5 (S)-2-(4-(4-bromophenyl)thiophene-2-carbonyl)-N-methyl-N-(4-(3-oxomorpholino)phenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide 
• 1394169-80-2 (S)-1-(4-(4-bromophenyl)thiophene-2-carbonyl)-N-methyl-N-(4-(2-oxopiperidin-1-yl)phenyl) piperidine-3-carboxamide 

Relevant academic research and scientific papers

Novel thiophene derivatives, their process of preparation and the pharmaceutical compositions which comprise them

A compound of formula (I) selected from: wherein: X represents oxygen or sulphur, Y represents oxygen, —NH— or —N(C1-C6)alkyl-, Ra represents hydrogen, halogen, (C1-C3)alkyl, hydroxyl or (C1-C3)alkoxy, Rb represents hydrogen, halogen or (C1-C3)alkyl, A represents phenyl, pyridyl, (C5-C6)cycloalkyl or (C5-C6)cycloalkenyl, R1 and R2 each represent a group selected from hydrogen, halogen, cyano, nitro, haloalkyl, haloalkoxy, alkyl, alkenyl, alkynyl, —OR4, —NR4R5, —S(O)nR4, —C(O)R4, —CO2R4, —O—C(O)R4, —C(O)NR4R5, —NR5—C(O)R4, —NR5—SO2R4, -T-CN, -T-OR4, -T-OCF3, -T- NR4R5, -T-S(O)nR4, -T-C(O)R4, -T-CO2R4, -T-O—C(O)R4, -T-C(O)NR4R5, -T-NR4—C(O)R5, -T-NR4—SO2R5, —R6 and -T-R6 in which n, T, R4, R5 and R6 are as defined in the description, R3 represents an —R7 or —U—R11 group in which R7 represents hydrogen, alkyl, aryl, cycloalkyl or heterocycle, U represents a linear or branched alkylene chain and R11 is defined in the description, their optical isomers or their addition salts with a pharmaceutically acceptable acid or base, and their use as inhibitor of metalloproteinase and more specifically of metalloproteinase-12.