26148-38-9

Usage

Classification

Aromatic amine

Physical state at room temperature

Dark grey to brown solid

Solubility in water

Sparingly soluble

Uses

Synthesis of pharmaceuticals, dyes, and other organic compounds

Potential applications

Anti-inflammatory and anti-cancer therapies

Health and environmental hazards

Considered hazardous to human health and the environment

Safety precautions

Proper safety measures should be taken when handling 1,2-Benzenediamine, N-2-pyridinyl-

Upstream product

• 109-09-1 2-chloropyridine 
• 95-54-5 1,2-diamino-benzene 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 25551-61-5 N-(2-nitrophenyl)-2-aminopyridine 
• 100-51-6 benzyl alcohol 
• 6631-37-4 2-(phenylamino)pyridine 
• 504-29-0 2-aminopyridine 
• 609-73-4 o-nitroiodobenzene 

Downstream Products

• 89659-78-9 [2-(Pyridin-2-ylamino)-phenyl]-carbamic acid ethyl ester 
• 244758-68-7 (E)-2-[2-(2-Furyl)ethenyl]-1-(2-pyridyl)-1H-benzimidazole 
• 371110-36-0 (E)-2-(3-Fluorostyryl)-1-(2-pyridyl)-1H-benzimidazole 
• 244758-61-0 (E)-1-(2-Pyridyl)-2-(4-methoxystyryl)-1H-benzimidazole 
• 244758-78-9 (Z)-2-(1-Fluoro-2-phenylethenyl)-1-(2-pyridyl)-1H-benzimidazole 
• 132278-01-4 (E)-4,4-dimethyl-2-pentenoyl chloride 
• 244758-66-5 (E)-2-[2-(Cyclohexyl)ethenyl]-1-(2-pyridyl)-1H-benzimidazole 
• 89659-87-0 1-methyl-3-(2-pyridyl)benzimidazolin-2-one 

Relevant academic research and scientific papers

Double N,B-Type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation

Boryl ligands hold promise in catalysis due to their very high electron-donating property. In this communication double N,B-type boryl anions were designed as bidentate ligands to promote an sp2 C-H borylation reaction. A symmetric pyridine-con

BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS

The present invention relates tobenzimidazole ethers and related compounds which are of use in the field of agriculture as fungicides.

The synthesis of benzimidazoles via a recycled palladium catalysed hydrogen transfer under mild conditions

An efficient synthesis of benzimidazoles was developed by virtue of a recycled palladium catalyzed hydrogen transfer. The reaction can be carried out smoothly under mild conditions to give rise to a variety of benzimidazoles with good to excellent yields. The palladium catalyst could be recovered easily and reused six times with great catalytic activity.

N,B-bidentate boryl ligand-supported iridium catalyst for efficient functional-group-directed C-H borylation

Convenient silylborane precursors for introducing N,B-bidentate boryl ligands onto transition metals were designed, prepared, and employed in ready formation of irdium(IIl) complexes via Si-B oxidative addition. A practical, efficient catalytic ortho-borylation reaction of arenes with a broad range of directing groups was developed using an in situ generated catalyst from the silylborane preligand 3c and [IrCl(COD)]2.

AGRICULTURAL CHEMICALS

The present invention relates to compounds which are of use in the field of agriculture as fungicides.

Cobalt-Catalyzed Regioselective Ortho C(sp2)-H Bond Nitration of Aromatics through Proton-Coupled Electron Transfer Assistance

A cobalt-catalyzed proton-coupled electron transfer (PCET) mediated regioselective ortho-specific nitration of aromatic C(sp2)-H bonds using chelation-assisted removable vicinal diamine directing groups was developed. The reaction proceeded under mild conditions in the presence of Co(OAc)2·4H2O as the catalyst with AgNO2 utilized as the nitro source as well as terminal oxidant in the presence of O2 as an external oxidant. No external base or additives were required for this process. Controlled experiments and mechanistic investigations with DFT calculations revealed that the reaction proceeds through a PCET promoted nitro functional group transfer pathway. Moreover, the produced compounds are valuable and pharmaceutically quite relevant.

Borane pyridine pre-ligand and its preparation method and application and method for preparing aryl borate (by machine translation)

The present invention provides a kind of borane pyridine pre-ligand and its preparation method and application and method for preparing aryl borate, the invention uses a relatively low price and easy to operate method for the synthesis of pyridine base bo

Synthesis and isolation of an acyclic tridentate bis(pyridine)carbodicarbene and studies on its structural implications and reactivities

The simple synthetic development of acyclic pincer bis(pyridine)carbodicarbene is depicted herein. Presented is the first isolated structural pincer carbodicarbene with a C-C-C angle of 143°, larger than the monodentate framework. More importantly, theore

ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE

The present invention is directed to aryl sulfamide derivatives of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.