26155-60-2Relevant academic research and scientific papers
Reaction of hydrazonoyl halides 511: A facile synthesis of 5-arylthiazoles and triazolino[4,3-a]pyrimidines as antimicrobial agents
Abdelhamid, Abdou O.,Sayed, Abdelwahed R.,Zaki, Yasser H.
, p. 1447 - 1457 (2007)
[5-Substituted 2-(3-phenyl-5-substituted 2-pyrazolinyl)(1,3-thiazol-4-yl)] phenyldiazenes, triazolo[3,4-a]pyrimidines, and 2,3-dihydro-1,3,4-thiadiazoles were synthesized with good yields from reactions of hydrazonoyl halides with 5-substituted-3-phenyl-4
Synthesis, antimicrobial and anticancer activity of new thiosemicarbazone derivatives
Kulandaivelu, Umasankar,Padmini, Valisakka Gari,Suneetha, Kyatham,Shireesha, Boyapati,Vidyasagar, Jannu Vincent,Rao, Tadikonda Rama,Jayaveera,Basu, Arijit,Jayaprakash, Venkatesan
experimental part, p. 84 - 90 (2011/09/21)
Thiosemicarbazones of p-aminobenzoic acid (PABA) were synthesized and tested for their antimicrobial and anticancer activity. Hydroxamate derivatives 4a-4l were found to have better antimicrobial and anticancer activity than their acid counterpart. Compound 4d was found to have good antimicrobial activity against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Vibrio cholerae, and Bacillus subtilis with IC50 value of about 1 aμM. Compound 4f showed potent antifungal activity against Candida albicans (IC50a=a1.29 aμM) and compound 4h showed potent anticancer activity (IC50a=a0.07 aμM). Hydroxamate derivatives 4a-4l were found to show better antimicrobial and anticancer activity in compariosn with their acid counterparts 3a-3l. Copyright
