2616-72-0

Basic information

• Product Name: NAPHTHOL AS-TR PHOSPHATE
• Synonyms: NAPHTHOL-AS-TR-PHOSPHATE extrapure;N-(4-Chloro-2-methylphenyl)-3-(phosphonooxy)-2-naphthalenecarboxamide;Chloro-2-methylphenyl)-3-(phosphonooxy)naphthalene-2-carboxamide;Naphthol AS-TR Phosphate,naphthol free;[3-[(4-chloro-2-methyl-phenyl)carbamoyl]-2-naphthyl] dihydrogen phosphate;[3-[(4-chloro-2-methyl-phenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate;[3-[(4-chloro-2-methylphenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate;Naphthol AS-TR Phosphate [for Biochemical Research]
• CAS NO: 2616-72-0
• Molecular Formula: C18H15ClNO5P
• Molecular Weight: 391.74
• EINECS: 220-046-7
• Product Categories: Alphabetical ListingImmunohistochemistry;PowdersWestern Blotting;Alkaline Phosphatase;Detection Substrates;Enzyme Substrates;Powders;Acid PhosphataseEnzyme Substrates;Substrates by Enzyme;Substrates
• Mol File: 2616-72-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.522g/cm³
• Refractive Index: 1.708
• Storage Temp.: 2-8°C
• PKA: 1.04±0.30(Predicted)
• BRN: 6666070
• CAS DataBase Reference: NAPHTHOL AS-TR PHOSPHATE(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHOL AS-TR PHOSPHATE(2616-72-0)
• EPA Substance Registry System: NAPHTHOL AS-TR PHOSPHATE(2616-72-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 2616-72-0(Hazardous Substances Data)

Usage

Uses

Naphthol AS-TR Phosphate is a novel composition useful for treating cancer.

InChI:InChI=1/C18H15ClNO5P/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24/h2-10H,1H3,(H,20,21)(H2,22,23,24)

Upstream product

• 95-69-2 4-chloro-2-methylbenzeneamine 
• 92-70-6 3-Hydroxy-2-naphthoic acid 
• 92-76-2 naphthol ASTR 

Relevant articles and documents

Fluorescent substrates for potential use in enzyme-linked immunosorbent assay of membrane-bound nucleic acids

A number of phosphorylated fluorochromes were synthesized and tested for the alkaline phosphatase-linked fluorescence assay of membrane-bound nucleic acids. 3-Hydroxy-N-2′-biphenyl-2-naphthalenecarboxamide phosphate ester (HBNP) was found to be the most suitable for the assay. Nonfluorescent HBNP is hydrolyzed by phospholipase bound to the probe DNA to the highly fluorescent 3-hydroxy-N,2′-biphenyl-2-naphthalenecarboxamide (HBN). HBN is insoluble enough in aqueous medium to precipitate on the nylon membrane. Spots containing as little as 5 fg of λ DNA can be successfully detected on the membrane with HBNP.