261617-75-8Relevant academic research and scientific papers
A convenient preparation of xanthene dyes
Yang, Youjun,Escobedo, Jorge O.,Wong, Alexander,Schowalter, Corin M.,Touchy, Michael C.,Jiao, Lijuan,Crowe, William E.,Fronczek, Frank R.,Strongin, Robert M.
, p. 6907 - 6912 (2007/10/03)
A facile synthetic route utilizing readily available reagents affords a series of regioisomerically pure xanthene dye derivatives. Advantages include relatively mild conditions and good to excellent yields. Nonpolar, highly crystalline intermediates are i
Specific and chemoselective multi-α-arylation reaction of benzoylformic acid with or without decarbonylation in P2O5-MsOH and related acidic media
Yonezawa, Noriyuki,Hino, Tetsuo,Matsuda, Kazuhisa,Matsuki, Toshiyuki,Narushima, Daisuke,Kobayashi, Masato,Ikeda, Tomiki
, p. 941 - 944 (2007/10/03)
In P2O5-MsOH, or related acidic media, benzoylformic acid (1) undergoes three types of di- or mono-α-arylation reactions with or without decarbonylation ((1) decarbonylative α,α-diarylation, yielding triarylmethanols 6, (2) decarbonylative α-monoarylation, giving benzophenone derivatives 7, and (3) α,α-diarylation without decarbonylation, affording diarylated carboxylic acids 5) and one simple decarbonylation, without arylation, to form benzoic acid (8), instead of the conventional Friedel- Crafts acylation type reaction. The product ratios are governed by the capability of the acidic medium to form mixed anhydrides with carboxylic acids and the ability of the arenes to accept electrophiles.
