26163-74-6 Usage
General Description
The chemical "(E)-3-(2-furyl)-1-morpholin-4-yl-prop-2-en-1-one" is a molecule with a furan ring, a morpholine ring, and a propenone chain. It is also known as Furanone C-30 and is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The furan ring provides aromaticity and stability to the molecule, while the morpholine ring and propenone chain contribute to its reactivity and potential biological activity. The molecule's chemical structure and functional groups make it a versatile building block for the synthesis of various complex organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 26163-74-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,1,6 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 26163-74:
(7*2)+(6*6)+(5*1)+(4*6)+(3*3)+(2*7)+(1*4)=106
106 % 10 = 6
So 26163-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO3/c13-11(12-5-8-14-9-6-12)4-3-10-2-1-7-15-10/h1-4,7H,5-6,8-9H2/b4-3+
26163-74-6Relevant articles and documents
Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors
Lin, Edward Yin-Shiang,Guckian, Kevin M.,Silvian, Laura,Chin, Donovan,Ann Boriack-Sjodin,van Vlijmen, Herman,Friedman, Jessica E.,Scott, Daniel M.
scheme or table, p. 5245 - 5248 (2009/05/08)
LFA-1 ICAM inhibitors based on ortho- and meta-phenol templates were designed and synthesized by Mitsunobu chemistry. The selection of targets was guided by X-ray co-crystal data, and led to compounds which showed an up to 30-fold increase in potency over reference compound 1 in the LFA-1/ICAM1-Ig assay. The most active compound exploited a new hydrogen bond to the I-domain and exhibited subnanomolar potency.
