26167-45-3

Basic information

• Product Name: 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one
• Synonyms: 1-BENZO[B]THIOPHEN-3-YL-2-BROMOETHAN-1-ONE;1-(1-BENZOTHIOPHEN-3-YL)-2-BROMO-1-ETHANONE;1-Benzo[b]thiophen-3-yl-2-bromoethan-1-on, 97%;3-(Bromoacetyl)benzo[b]thiophene 97%;1-(Benzo[b]thiophen-3-yl)-2-bromoethan-1-one97%;3-(Bromoacetyl)benzo[b]thiophene;3-(Bromoacetyl)benzothiophene;1-(1-benzothiophen-3-yl)-2-broMoethan-1-one
• CAS NO: 26167-45-3
• Molecular Formula: C₁₀H₇BrOS
• Molecular Weight: 255.13
• Mol File: 26167-45-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 138 °C
• Boiling Point: 352 °C at 760 mmHg
• Flash Point: 166.7 °C
• Appearance: /
• Density: 1.617 g/cm³
• Vapor Pressure: 3.96E-05mmHg at 25°C
• Refractive Index: 1.689
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one(26167-45-3)
• EPA Substance Registry System: 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one(26167-45-3)

Safety Data

• Hazard Codes: C
• Statements: 36/37/38-34
• Safety Statements: 26-36/37/39-45-26/37/39
• RIDADR: 3261
• HazardClass: IRRITANT
• Hazardous Substances Data: 26167-45-3(Hazardous Substances Data)

Usage

Chemical Properties

Gray solid

Uses

1-(Benzo[b]thiophen-3-yl)-2-bromoethanone is one of the thiazole analogs of indomethacin as selective COX-2 inhibitors.

InChI:InChI=1/C10H7BrOS/c11-5-9(12)8-6-13-10-4-2-1-3-7(8)10/h1-4,6H,5H2

Upstream product

• 1128-05-8 3-acetylbenzothiophene 
• 95-15-8 Benzo[b]thiophene 

Downstream Products

• 855292-15-8 1-benzo[b]thiophen-3-yl-2-phenylsulfanyl-ethanone 

Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

Baker's yeast-mediated synthesis of (R)- and (S)-heteroaryl-ethane-1,2-diols

Baker's yeast-mediated enantioselective bioreduction of 1-(heteroaryl)-2-hydroxyethanones and 2-acetoxy-1-(hetero-aryl)ethanones was used for the enantioselective synthesis of both (R)- and (S)-benzofuranyl-, benzo[b]thiophenyl- and benzo[d]thiazolyl-ethane-1,2-diols.

Condensed thiazole derivatives, having 5-HT receptor affinity

Compounds of formula I STR1 in which A is S(O) p or O;p is 0, 1 or 2;g is 0, 1, 2, 3, or 4;n is 2 or 3; andR 1, R 2, R 3, R 4 and R 5 are optional substituents have utility in the treatment of central nervous system disorders, for example depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, obesity, drug addiction, drug abuse, cognitive disorders, Alzheimer''s disease, senile dementia, cerebral ischemia, obsessive-compulsive behavior, panic attacks, social phobias, eating disorders and anorexia, non-insulin dependent diabetes mellitus, hyperglycemia, and stress.