261712-09-8

Basic information

• Product Name: 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine
• Synonyms: 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine
• CAS NO: 261712-09-8
• Molecular Weight: 221.326
• Mol File: 261712-09-8.mol

Chemical Properties

• CAS DataBase Reference: 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine(261712-09-8)
• EPA Substance Registry System: 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine(261712-09-8)

Safety Data

• Hazardous Substances Data: 261712-09-8(Hazardous Substances Data)

Upstream product

• 261711-98-2 N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide 
• 5369-19-7 3-tert-butylaniline 
• 142564-53-2 5-(tert-butyl)-2-nitroaniline 
• 261712-05-4 5-tert-Butyl-2-nitro-4-thiocyanato-phenylamine 

Downstream Products

• 261712-19-0 toluene-4-thiosulfonic acid S-(4,5-bis-tert-butoxycarbonylamino-2-tert-butyl-phenyl) ester 
• 261712-35-0 (2-tert-butoxycarbonylamino-4-tert-butyl-5-mercapto-phenyl)-carbamic acid tert-butyl ester 
• 261712-23-6 Toluene-4-thiosulfonic acid S-(4,5-diamino-2-tert-butyl-phenyl) ester 
• 261712-13-4 (2-tert-butoxycarbonylamino-4-tert-butyl-5-thiocyanato-phenyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

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The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.

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