261727-70-2

Upstream product

• 40930-93-6 2,5-bis(benzyloxy)-4-methyl-benzaldehyde 
• 261727-61-1 3-{[2,5-Bis(benzyloxy)-4-methylphenyl]methyl}-pentan-2,4-dion 
• 261727-59-7 3-[2,5-Bis(benzyloxy)-4-methylbenzyliden]pentan-2,4-dion 
• 123-54-6 acetylacetone 
• 116626-41-6 (2,5-Dibenzyloxy-4-methyl-phenyl)-methylchlorid 
• 261727-65-5 (Z)-4-Amino-3-{[2,5-bis(benzyloxy)-4-methyl-phenyl]-methyl}-pent-3-en-2-on 

Downstream Products

• 261727-75-7 (Z)-2-[(4-Amino-2-oxo-pent-3-en-3-yl)-methyl]-5-methyl-cyclohexa-2,5-dien-1,4-dion 

Relevant academic research and scientific papers

Investigation on the formation of 6-hydroxyindole in the nenitzescu reaction. VI. Cyclization of β-[(1,4-quinon-2-yl)methyl]-enaminon derivatives

Starting from 2,5-bisbenzyloxy-4-methyl-benzaldehyd 2-(3-amino-2-acetyl-but-2-enyl)-5-methyl[1,4]benzoquinones 9a-e are synthesized as model compounds in order to study the ambident reactivity of enaminones and quinones. Spontaneus cyclization of 9b-e in ethanol or acetic acid to 1-aza-spiro[4,5]deca-2,7-dien-6,9-dion 20b-e in good yield is observed. 6-Hydroxy-3-acetyl-quinoline 21 is obtained from 9a. In one case (9c) 2-acetyl-3-benzylamino-7-hydroxy-naphthalene (17) was formed as by-product. 9d in alkoholic perchloric acid leads to quinolinium salt 18 in low yield. Wiley-VCH Verlag GmbH, 2000.