261761-55-1

Basic information

• Product Name: 2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE
• Synonyms: 2,3-DICHLOROBENZAMIDOXIME;2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE;2,3-Dichloro-N-hydroxybenzamidine;2,3-Dichloro-N-hydroxybenzimidamide
• CAS NO: 261761-55-1
• Molecular Formula: C₇H₆Cl₂N₂O
• Molecular Weight: 205.04
• Mol File: 261761-55-1.mol

Chemical Properties

• Melting Point: 141-144
• Appearance: /
• CAS DataBase Reference: 2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(261761-55-1)
• EPA Substance Registry System: 2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(261761-55-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 261761-55-1(Hazardous Substances Data)

Usage

Uses

Used in Agriculture:
2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE is used as a herbicide for controlling the growth of unwanted plants in agricultural fields. It is applied to inhibit photosynthesis, thereby preventing the growth and survival of weeds and other unwanted vegetation.
Used in Non-Agricultural Settings:
2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE is used as a herbicide in non-agricultural settings such as industrial sites and residential areas to control the growth of unwanted plants and maintain a clean and tidy environment.
However, due to its persistence in the environment and potential for runoff into water sources, leading to detrimental effects on aquatic organisms, 2,3-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE is considered a potential environmental hazard. As a result, its use is heavily regulated in many countries to minimize its impact on ecosystems and water sources.

Upstream product

• 886501-33-3 2-chloro-3,6-difluoro-benzonitrile 
• 6574-97-6 2,3-dichlorobenzonitrile 

Downstream Products

• 1046113-97-6 3-(2,3-dichloro-phenyl)-5-{(E)-2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-vinyl}-1,2,4-oxadiazole trifluoroacetate 

Relevant articles and documents

Synthesis and Biological Evaluation of Sigma-1 (σ1) Receptor Ligands Based on Phenyl-1,2,4-oxadiazole Derivatives

In this study, a series of phenyl-1,2,4-oxadiazole derivatives were synthesized and evaluated for anti-allodynic activity. Structure–activity relationship studies identified 1-{4-[3-(2,4-dichlorophenyl)-1,2,4-oxadiazol-5-yl]butyl}piperidine (39) with excellent affinity for the σ1 receptor and selectivity for the σ2 receptor, with poor activity to other central nervous system neurotransmitter receptors and transporters associated with pain. Compound 39 exhibited dose-dependent efficacy in suppressing the formalin-induced flinching and attenuating mechanical allodynia in chronic constriction injury-induced neuropathic rats. These results suggest that compound 39 exerts potent antihyperalgesic activity and could be considered as a promising candidate for treating neuropathic pain.

PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE

The present application relates to novel substituted piperidinylpyrazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired hemostatic disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of heavy menstrual bleeding, postpartum hemorrhage, hemorrhagic shock, hemorrhagic cystitis, gastrointestinal hemorrhage, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.

HETEROARYL SUBSTITUTED DIAZABICYCLONONENE DERIVATIVES

The invention relates to heteroaryl substituted diazabicyclononene derivatives, related compounds and use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for

NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention relates to novel compounds of formula (I) wherein W, n, X and W’ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 (“mGluR5”) which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.

Structure-activity relationships of acyloxyamidine cytomegalovirus DNA polymerase inhibitors

This paper describes the structure-activity relationships of a new class of cytomegalovirus DNA polymerase inhibitors having two aryl groups joined by an acyloxyamidine linker. Examination of a series of analogues in which the terminal groups are varied r