261766-24-9

Basic information

• Product Name: INDOMETHACIN ESTER, 4-METHOXYPHENYL-
• Synonyms: INDOMETHACIN ESTER, 4-METHOXYPHENYL-;1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID, 4-METHOXYPHENYL ESTER
• CAS NO: 261766-24-9
• Molecular Formula: C26H22ClNO5
• Molecular Weight: 463.91
• Mol File: 261766-24-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: INDOMETHACIN ESTER, 4-METHOXYPHENYL-(CAS DataBase Reference)
• NIST Chemistry Reference: INDOMETHACIN ESTER, 4-METHOXYPHENYL-(261766-24-9)
• EPA Substance Registry System: INDOMETHACIN ESTER, 4-METHOXYPHENYL-(261766-24-9)

Safety Data

• Hazardous Substances Data: 261766-24-9(Hazardous Substances Data)

Usage

Uses

Indomethacin Ester, 4-Methoxyphenyl- is a potent and selective inhibitor of COX-2.

Upstream product

• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase

Carboxylesterase (CES) plays an important role in the hydrolysis metabolism of ester–type drugs and prodrugs. In this study, we investigated the change in the hydrolysis rate of hCE1 by focusing on the steric hindrance of the ester structure and the elect