261776-88-9

Upstream product

• 34536-05-5 4-Amino-7-(2-deoxy-β-D-erythro-pentafuranosyl)-7H-imidazo[4,5-d][1,2,3]triazine 
• 68498-25-9 3-(2-Deoxy-β-D-erythro-pentafuranosyl)-3H-imidazo[2,1-i]purine 
• 958-09-8 2'-deoxy-D-adenosine 
• 151229-13-9 1-(2-Deoxy-β-D-erythro-pentafuranosyl)-5-amino-4-(imidazol-2''-yl)imidazole 
• 261776-85-6 3-(2-Deoxy-β-D-erythro-pentafuranosyl)-1H-diimidazo[1,2-c:4',5'-e][1,2,3]triazine 
• 19449-30-0 N,N-dibutylformamide dimethyl acetal 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 261776-97-0 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-{[(di-n-butylamino)methylidene]amino}-7H-imidazo[4,5-d][1,2,3]triazine 

Relevant academic research and scientific papers

2-AZAPURINE COMPOUNDS AND THEIR USE

Within oligonucleotides 2-azapurine and especially 2-azaadenine bases form specifically base pairs with guanine. This base pair is of analogous stability as an adenine-thymine but less stable than a guanine-cytosine base pair. Therefore, the incorporation

2-aza-2′-deoxyadenosine: Synthesis, base-pairing selectivity, and stacking properties of oligonucleotides

2-Aza-2′-deoxyadenosine (2, z2Ad) is synthesized via its 1,N6-etheno derivative 7 and enzymatically deaminated to 2-aza-2′-deoxyinosine (3). Compound 2 is converted into the phosphoramidite building block 10b. This is empl