261917-70-8

Basic information

• Product Name: 3,3-Dimethyl-6,6-diphenyl-3,4,5,6-tetrahydropyridine
• CAS NO: 261917-70-8
• Molecular Weight: 263.382
• Mol File: 261917-70-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3-Dimethyl-6,6-diphenyl-3,4,5,6-tetrahydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dimethyl-6,6-diphenyl-3,4,5,6-tetrahydropyridine(261917-70-8)
• EPA Substance Registry System: 3,3-Dimethyl-6,6-diphenyl-3,4,5,6-tetrahydropyridine(261917-70-8)

Safety Data

• Hazardous Substances Data: 261917-70-8(Hazardous Substances Data)

Upstream product

• 20633-35-6 4-[1,3]dioxolan-2-yl-4-methyl-pentanenitrile 
• 591-51-5 phenyllithium 

Relevant articles and documents

Synthesis of novel pipecolic acid derivatives: A multicomponent approach from 3, 4, 5, 6-tetrahydropyridines

A simple approach to several derivatives of pipecolic acid is via a multicomponent reaction starting from cyclic imines 2, which are synthesized on a large scale and with different substitution patterns. The protected amino acids 3 are formed in high yields. In cases where chiral imines are used the target compounds are obtained with remarkable diastereoselectivity. Bisamides 3 serve as versatile precursors for the preparation of a wide range of amino acid derivatives. Different methods of hydrolysis of 3 lead to the free pipecolic acids or its derivatives. Employment of methanol or ethanethiol as a nucleophile in the acid-mediated conversion of enamides 3 results in W-acylated amino acid esters 5. Furthermore a method for the resolution of the obtained racemic a-amino acids via diastereomeric salt formation is described. The Royal Society of Chemistry 1999.