2620-53-3

Basic information

• Product Name: (4-chlorophenyl) N-methylcarbamate
• Synonyms: (4-chlorophenyl) N-methylcarbamate;CARBAMICACID,METHYL-,4-CHLOROPHENYLESTER;PARA-CHLOROPHENYL-N-METHYLCARBAMATE;Mephenate;N-Methylcarbamic acid (4-chlorophenyl) ester;PPG-124
• CAS NO: 2620-53-3
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.6076
• Mol File: 2620-53-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 115-116 °C(Solv: methanol (67-56-1); ethanol (64-17-5); octane (111-65-9))
• Boiling Point: 254 °C at 760 mmHg
• Flash Point: 107.4 °C
• Appearance: /
• Density: 1.255 g/cm³
• Vapor Pressure: 0.0177mmHg at 25°C
• Refractive Index: 1.535
• PKA: 11.83±0.46(Predicted)
• CAS DataBase Reference: (4-chlorophenyl) N-methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl) N-methylcarbamate(2620-53-3)
• EPA Substance Registry System: (4-chlorophenyl) N-methylcarbamate(2620-53-3)

Safety Data

• Hazardous Substances Data: 2620-53-3(Hazardous Substances Data)

Usage

General Description

(4-chlorophenyl) N-methylcarbamate is a chemical compound that is used as a pesticide and insecticide. It works by inhibiting the activity of the enzyme acetylcholinesterase, causing an accumulation of the neurotransmitter acetylcholine at nerve synapses. This leads to overstimulation of the nervous system in insects, ultimately resulting in paralysis and death. However, the use of (4-chlorophenyl) N-methylcarbamate has been linked to environmental and health concerns, with studies showing potential negative impacts on non-target organisms and human health. Due to these concerns, the use of this chemical has been restricted or banned in some countries.

InChI:InChI=1/C8H8ClNO2/c1-10-8(11)12-7-4-2-6(9)3-5-7/h2-5H,1H3,(H,10,11)

Upstream product

• 123-39-7 N-Methylformamide 
• 106-48-9 4-chloro-phenol 
• 14128-35-9 N-methylthiocarbamic acid O-methyl ester 
• 30379-59-0 benzyl N-methylcarbamate 
• 25070-81-9 allyl N-methylcarbamate 
• 6642-30-4 methyl N-methylcarbamate 
• 624-83-9 methyl isocyanate 

Downstream Products

• 39074-30-1 Chloromethyl-methyl-carbamic acid 4-chloro-phenyl ester 

Relevant articles and documents

Ligand-assisted copper-catalyzed oxidative cross-coupling of simple phenols with formamides for the synthesis of carbamates

An oxidative approach for the synthesis of phenyl carbamates has been achieved by ligand-assisted copper-catalyzed cross-dehydrogenative coupling (CDC) of phenols with formamides. The direct coupling of simple phenols with mono- and dialkyl formamides pro

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from Euryarchaeota belonging to the family Picrophilaceae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the subfamily Synechococcoideae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.