2620-53-3

Usage

Uses

Used in Agricultural Industry:
(4-chlorophenyl) N-methylcarbamate is used as a pesticide and insecticide for controlling a wide range of pests, including soil-dwelling insects, in various crops such as cotton, soybeans, and ornamental plants. Its application reason is its ability to inhibit the activity of the enzyme acetylcholinesterase, leading to an accumulation of the neurotransmitter acetylcholine at nerve synapses in insects. This causes overstimulation of the nervous system, resulting in paralysis and death of the pests.
Environmental and Health Concerns:
Despite its effectiveness as a pesticide, (4-chlorophenyl) N-methylcarbamate has been linked to several environmental and health issues. Studies have shown that it can have negative impacts on non-target organisms, such as beneficial insects, birds, and aquatic life. Additionally, there are concerns about its potential effects on human health, including acute poisoning and long-term exposure risks. As a result, the use of this chemical has been restricted or banned in some countries to protect the environment and public health.

InChI:InChI=1/C8H8ClNO2/c1-10-8(11)12-7-4-2-6(9)3-5-7/h2-5H,1H3,(H,10,11)

Upstream product

• 106-48-9 4-chloro-phenol 
• 624-83-9 methyl isocyanate 
• 6642-30-4 methyl N-methylcarbamate 
• 25070-81-9 allyl N-methylcarbamate 
• 30379-59-0 benzyl N-methylcarbamate 
• 123-39-7 N-Methylformamide 
• 14128-35-9 N-methylthiocarbamic acid O-methyl ester 

Downstream Products

• 39074-30-1 Chloromethyl-methyl-carbamic acid 4-chloro-phenyl ester 

Relevant academic research and scientific papers

Ligand-assisted copper-catalyzed oxidative cross-coupling of simple phenols with formamides for the synthesis of carbamates

An oxidative approach for the synthesis of phenyl carbamates has been achieved by ligand-assisted copper-catalyzed cross-dehydrogenative coupling (CDC) of phenols with formamides. The direct coupling of simple phenols with mono- and dialkyl formamides pro

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from protists belonging to the family Blepharismidae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from Euryarchaeota belonging to the family Picrophilaceae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Kordia, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the subfamily Synechococcoideae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Plants Tolerant to HPPD Inhibitor Herbicides

The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Rhodococcus as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

One-pot, three-step preparation of alkyl and aryl alkylcarbamates from S-methyl N-alkylthiocarbamates

A general procedure for the synthesis of alkyl and aryl alkylcarbamates starting from the corresponding 5-methyl N-alkylthiocarbamates is described. This procedure consists of three steps that are carried out in a one-pot fashion, without isolating the intermediate N-alkylcarbamoyl chlorides or alkyl isocyanates. All the target products were obtained in high yields (16 examples, average yield 91%). To be noted is the recovery of a co-product of industrial interest, dimethyl disulfide, in a half mole amount for each mole of thiocarbamate, with complete exploitation of the reagent. The alkyl isocyanates, if required, can also be isolated in high yields. Georg Thieme Verlag Stuttgart.

Active substances for increasing the stress defense in plants to abiotic stress, and methods of finding them

The invention relates to a method of finding compounds which increase the tolerance of plants to abiotic stress factors acting on this plant, such as, for example, temperature (such as chill, frost or heat), water (such as dryness, drought or anoxia), or the chemical load (such as lack of or excess of mineral salts, heavy metals, gaseous noxious substances) by increasing the expression of plant-endogenous proteins, and to the use of these compounds for increasing the tolerance in plants to abiotic stress factors.

Concomitant Desulfurization and Transesterification of Alkyl Thionocarbamates

Alkyl carbamate (such as 1) reacts with triphosgene at the nitrogen atom, whereas the analogous thionocarbamates (5) react at the sulfur. Subsequent treatment with various phenols or alcohols leads to the corresponding aryl carbamates or alkyl carbamates

Transesterification of alkyl carbamate to aryl carbamate : Effect of varying the alkyl group

Phosphorus oxychloride mediated transesterification of four alkyl N-methylcarbamates to several aryl N-methylcarbamates has been studied. Best yields are obtained from benzyl N-methylcarbamate.