26210-77-5Relevant academic research and scientific papers
Dihydrobenzofuran production from catalytic tandem Claisen rearrangement-intramolecular hydroaryloxylation of allyl phenyl ethers in subcritical water
Luo, Ligang,Liu, Chunze,Hou, Zhiqiang,Wang, Yuanyuan,Dai, Liyi
, p. 29527 - 29533 (2014/08/05)
We herein report a mild method for the preparation of dihydrobenzofurans through hydrothermal catalytic tandem Claisen rearrangement-intramolecular hydroaryloxylation of allyl phenyl ethers. This reaction provides a new method for constructing dihydrobenzofurans, a process that is potentially applicable to natural product synthesis. SBA-15, TS-1, HZSM-5 were chosen as catalysts in a hydrothermal reaction medium between 200 and 320 °C. HZSM-5 catalyst showed the highest catalytic activity, and the effects of molar ratio of allyl phenyl ether-water, time, pressure, temperature and catalyst on the Claisen hydroaryloxylation in hydrothermal condition were investigated. The latter two process variables had the greatest influence on the product yields and distribution. A series of allyl phenyl ether derivatives were also treated in hydrothermal condition with HZSM-5 catalyst to offer high yield of corresponding dihydrobenzofurans.
SYNTHESIS OF AMINO-SUBSTITUTED 2-METHYLCOUMARINS, CHROMANS, AND BENZOXEPANES AND THEIR N-(ALKYLAMINOACYL) DERIVATIVES
Daukshas, V. K.,Pyatrauskas, O. Yu.,Purvanyatskas, G. N.
, p. 266 - 270 (2007/10/02)
The isomeric compositions of the products of nitration of 2-methylcoumaran and chroman with acetyl nitrate were determined.More convenient methods for the synhtesis of 7-amino-2-methylcoumaran and 8-aminochroman were developed, and 9-amino-1-benzoxepane was obtained for the first time.Alkylaminoacylaminosubstituted 2-methylcoumarans, chromans, and 1-benzoxepanes were synthesized.A method for the synthesis of 2-bromocaproyl chloride from caproic acid was developed.
