2622-53-9Relevant academic research and scientific papers
P4VPy–CuO nanoparticles as a novel and reusable catalyst: application at the protection of alcohols, phenols and amines
Shirini, Farhad,Fallah-Shojaei, Abdollah,Abedini, Masoumeh,Samavi, Laleh
, p. 1699 - 1712 (2016/07/27)
P4VPy–CuO nanoparticles were synthesized using ultrasound irradiations. Relevant properties of the synthesized nanoparticles were investigated by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. After identification, the prepared reagent was used for the promotion of different types of protection reactions of alcohols, phenols and amines. Easy workup, short reaction times, excellent yields, relatively low cost and reusability of the catalyst are the striking features of the reported methods.
Nucleophilic allylation of N,O-acetals with allylic alcohols promoted by Pd/Et3B and Pd/Et2Zn systems
Yamaguchi, Yumi,Hashimoto, Mariko,Tohyama, Katsumi,Kimura, Masanari
supporting information; experimental part, p. 913 - 915 (2011/03/21)
Pd/Et3B and Pd/Et2Zn systems promote the nucleophilic allylations of 2-aminotetrahydrofuran and 2-aminotetrahydropyran with allylic alcohols to provide ω-hydroxyhomoallylamines in high yields. The transformation is applicable to the
Nickel-catalyzed multi-component connection reaction of isoprene, aldimines (lactamines), and diphenylzinc
Kojima, Keisuke,Kimura, Masanari,Ueda, Satoshi,Tamaru, Yoshinao
, p. 7512 - 7520 (2007/10/03)
Ni(acac)2 catalyzes the four-component connection reaction of diphenylzinc, isoprene, aromatic aldehydes, and aromatic amines in this order and provides stereochemically homogeneous (E)-1-arylamino-1-aryl-3-methyl-5-phenyl-3-pentenes (1) in excellent yields. Aliphatic aldehydes react similarly and give (E)-1-arylamino-1-alkyl-3-methyl-5-phenyl-3-pentenes (1) in slightly reduced yields. When the alkyl groups are bulky, in addition to 1 are formed (E)-1-arylamino-1-alkyl-4-methyl-5-phenyl-3-pentenes (1′) as the minor products. Lactamines prepared in situ from five- and six-membered lactols and aromatic amines are more reactive than alkyl aldehyde aldimines and furnish (E)-4-arylamino-6-methyl-8-phenyl-6-octen-1-ols (4) and (E)-5-arylamino-7-methyl-9- phenyl-7-nonen-1-ols (5), respectively, in good yields with excellent E-stereoselectivity.
Dimethylzinc-initiated radical reaction of cyclic ethers with arylamines, alkoxyamines, and dialkylhydrazines
Yamamoto, Yasutomo,Maekawa, Masaru,Akindele, Tito,Yamada, Ken-Ichi,Tomioka, Kiyoshi
, p. 379 - 384 (2007/10/03)
Dimethylzinc-initiated radical reaction of THF with arylamines afforded aminoalcohols which were derived from the two molecules of THF and one molecule of an arylamine. The reaction seems to proceed via two-consecutive processes, electrophilic and then nucleophilic reactions of THF-derived species. Alkoxyamines and dialkylhydrazines reacted with electrophilic cyclic ether species to give the corresponding oximes and hydrazones of ω- hydroxyalkanal.
Palladium-catalyzed addition of R2NH to double bonds. Synthesis of α-amino tetrahydrofuran and pyran rings
Cheng,King Kuok Hii
, p. 5445 - 5450 (2007/10/03)
Efficient addition of R1R2NH to unsaturated heterocycles has been achieved using palladium catalysts. The methodology was applied to the synthesis of a number of α-amino tetrahydrofurans and pyrans. Nature of amine, ring size and cat
