262278-79-5

Basic information

• Product Name: (+/-)-3-[(8-Chloro-4-oxo-4H-quinolizine-3-carbonyl)-amino]-3-phenyl-propionic acid ethyl ester
• Synonyms: (+/-)-3-[(8-Chloro-4-oxo-4H-quinolizine-3-carbonyl)-amino]-3-phenyl-propionic acid ethyl ester
• CAS NO: 262278-79-5
• Molecular Weight: 398.846
• Mol File: 262278-79-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-3-[(8-Chloro-4-oxo-4H-quinolizine-3-carbonyl)-amino]-3-phenyl-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-3-[(8-Chloro-4-oxo-4H-quinolizine-3-carbonyl)-amino]-3-phenyl-propionic acid ethyl ester(262278-79-5)
• EPA Substance Registry System: (+/-)-3-[(8-Chloro-4-oxo-4H-quinolizine-3-carbonyl)-amino]-3-phenyl-propionic acid ethyl ester(262278-79-5)

Safety Data

• Hazardous Substances Data: 262278-79-5(Hazardous Substances Data)

Upstream product

• 139161-20-9 ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate 
• 139160-79-5 8-chloro-4-oxo-4H-quinolizine-3-carboxylic acid 
• 29754-04-9 ethyl 3-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 262278-81-9 (+/-)-3-{[8-(2-tert-butoxycarbonylamino-ethylamino)-4-oxo-4H-quinolizine-3-carbonyl]-amino}-3-phenyl-propionic acid ethyl ester 

Relevant articles and documents

Quinolizinones as integrin inhibitors

The present invention is directed towards novel compounds that are effective inhibitors of integrins, particularly αIIbβ3 or αv integrins such as αvβ3 and αvβ5. One embodiment of the present invention comprises a compound of formula (I) or formula (II) or a pharmaceutically acceptable salt, solvate, or metabolic precursor thereof. R1, R2, R3, and R4 are defined herein.