262353-34-4

Basic information

• Product Name: 2,4-DIIODOPYRIMIDINE
• Synonyms: 2,4-DIIODOPYRIMIDINE
• CAS NO: 262353-34-4
• Molecular Formula: C₄H₂I₂N₂
• Molecular Weight: 331.874
• Product Categories: Pyrazines, Pyrimidines & Pyridazines;Halides;Pyrazines, Pyrimidines & Pyridazines;Heterocycle-Pyrimidine series
• Mol File: 262353-34-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 125-126 °C
• Boiling Point: 365.115 °C at 760 mmHg
• Flash Point: 174.615 °C
• Appearance: /
• Density: 2.765 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.737
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2.60±0.20(Predicted)
• CAS DataBase Reference: 2,4-DIIODOPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIIODOPYRIMIDINE(262353-34-4)
• EPA Substance Registry System: 2,4-DIIODOPYRIMIDINE(262353-34-4)

Safety Data

• Hazardous Substances Data: 262353-34-4(Hazardous Substances Data)

Usage

General Description

2,4-DIIODOPYRIMIDINE is a chemical compound with the molecular formula C4H2I2N2. It is a pyrimidine derivative that contains two iodine atoms attached to the pyrimidine ring. 2,4-DIIODOPYRIMIDINE has been used as a building block in the synthesis of various organic compounds. It is known for its ability to undergo substitution reactions, making it useful in the preparation of complex organic molecules. 2,4-DIIODOPYRIMIDINE has found applications in pharmaceutical and agrochemical industries as well as in academic research for its unique reactivity and potential for creating new chemical structures.

InChI:InChI=1/C4H2I2N2/c5-3-1-2-7-4(6)8-3/h1-2H

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 

Downstream Products

• 262353-35-5 2-iodo-4-methoxypyrimidine 
• 25095-48-1 2,4-diphenylpyrimidine 
• 53618-63-6 2-iodo-4-phenylpyrimidine 
• 1018473-97-6 2,4-bis-phenylethynylpyrimidine 
• 1018473-98-7 2,4-bis-4-(N,N-dimethylamino)phenylethynylpyrimidine 
• 1450722-43-6 2,4-bis-[4-(2,6-diphenyl-pyran-4-ylidenemethyl)-phenylethynyl]-pyrimidine 

Relevant articles and documents

Pyrimidine Derivatives with Terminal Pyridyl Heterocycles: Facile Synthesis and Their Antiproliferative Activities

Incorporation of heterocyclic pyrimidine or pyridine motifs is common in the drug design for various therapeutic applications. Herein, we describe the facile synthesis of two molecules containing both pyrimidine and pyridine scaffolds. A variety of analytical techniques (multinuclear NMR, Fourier transform infrared, and mass spectrometry analyses) confirmed the purity of these molecules. In pristine form, their potential as antitumor drugs was screened by investigating their cytotoxicity against various cell lines (cancerous and normal cells). Experimental results confirmed that the two molecules exhibited cell growth inhibition at very low concentrations. This was evident from their IC50 values that are in the range of 0.45–2.20 μM.

Bis- and tris(arylethynyl)pyrimidine oligomers: synthesis and light-emitting properties

In this contribution, we describe the synthesis of bis- and tris(arylethylnyl)pyrimidine oligomers using Sonogashira, Negishi and Suzuki cross-coupling reactions and starting from chloro or iodopyrimidines. When the arms of such banana-shaped and star-sha

First study of syntheses and reactivity of Grignard compounds in the diazine series. Diazines. Part 27

A preparation of Grignard derivatives of diazines is described using a halogen magnesium exchange reaction. This convenient method allows the functionalization of these rings at 0°C or even room temperature.