262360-92-9

Upstream product

• 123-91-1 1,4-dioxane 
• 32404-28-7 (S)-3-(3-acetyl-4-hydroxyphenyl)-2-aminopropanoic acid hydrochloride 
• 501-53-1 benzyl chloroformate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 32483-30-0 3-acetyl-L-tyrosine 

Downstream Products

• 1150635-46-3 L-N-Cbz-3-acetyl-5-iodotyrosine methyl ester 

Relevant academic research and scientific papers

Synthesis of L-3-hydroxy-4-methoxy-5-methylphenylalanol

The L-3-hydroxy-4-methoxy-5-methylphenylalanol, a common subunit of ecteinascidin and safracin family alkaloids, was synthesized from L-tyrosine in eight steps with an overall yield of 50%. Georg Thieme Verlag Stuttgart.

Ethylamine derivatives

The object of the present invention is to provide ethylamine derivatives that function as a motilin receptor antagonist and that are useful as medicines. The invention provides compounds represented by the general formula (1): wherein R1represents a phenyl group or the like, R2represents a hydrogen atom and the like, R3represents a hydrogen atom and the like, R4represents a hydrogen atom and the like, R5represents an alkyl group and the like, R7represents a hydrogen atom and the like and R8represents a heterocyclic ring and the like; or a hydrate or pharmaceutically acceptable salt thereof and a medicine which comprises the above compound or a hydrate or pharmaceutically acceptable salt thereof as an active ingredient.