26251-63-8Relevant articles and documents
Synthesis and anticancer activity of thiosemicarbazones
Hu, Wei-Xiao,Zhou, Wei,Xia, Chun-Nian,Wen, Xi
, p. 2213 - 2218 (2007/10/03)
Twenty-six thiosemicarbazones (III-1-III-26) were synthesized via three steps starting from hydrazine hydrate and carbon disulfide. The testing of anticancer activity of these compounds in vitro against P-388, A-549, and SGC-7901 shows that compounds III-15 and III-16 possess a higher inhibitory ability for P-388 and SGC-7901. Further testing shows that the value of IC 50 of compound III-16 against SGC-7901 reaches to 0.032 μM.