26257-31-8Relevant academic research and scientific papers
Synthesis of dibenzo(b,g)-5-methyl-1,8-naphthyridines
Kidwai,Kohli
, p. 248 - 249 (2007/10/03)
A series of 1,8-naphthyridines have been synthesised. 2-Hydroxy-4-methylquinoline 1 on reaction with PCI5/POCl3 gives 2-chloro-4-methylquinoline 2 which on treatment with substituted anilines yields 2-quinolinamines 3a-e. Cyclisation in situ affords the title compounds 4a-e using phosphorus oxychloride and dimethyl formamide.
