26259-22-3Relevant academic research and scientific papers
NiII-mediated coupling between iminoisoindolinones and nitriles leading to unsymmetrical 1,3,5-triazapentadienato complexes
Gushchin, Pavel V.,Luzyanin, Konstantin V.,Kopylovich, Maximilian N.,Haukka, Matti,Pombeiro, Armando J. L.,Kukushkin, Vadim Yu.
, p. 3088 - 3094 (2009/02/01)
Treatment of nickel acetate Ni(OAc)2·4H2O with 2 equiv of various 3-iminoisoindolin-1-ones in a suspension of RCN in the presence of triethanolamine leads to the formation of the nickel 1,3,5-triazapentadienato complexes [Ni{NH=C(R)N=C(C6R 1R2R3R4CON)}2] (1-17) isolated in good 50-83% yields. The reaction proceeds under relatively mild conditions (from 5 to 7 h at 25-115°C, depending on the boiling point of the nitrile) and has a general character insofar as it was successfully conducted with various nitriles RCN bearing donor (R = Me, Et, Prn, Pr i, Bun), weak donor (R = CH2Ph, CH 2C6H4OMe-p), acceptor (R = CH2Cl), and strong acceptor (R = CCl3) groups R of different steric hindrance and also with the nonsubstituted iminoisoindolinone (3-iminoisoindolin-1-one) or the iminoisoindolinones bearing donor methyl (3-imino-5-methylisoindolin-1- one) or acceptor fluoro (4,5,6,7-tetrafluoro-3-iminoisoindolin-1-one) groups in the benzene ring.
