262606-90-6Relevant articles and documents
A novel approach to conformationally restricted analogues of nicotine and anabasine by an intramolecular Hamaguchi-Ibata reaction
Sarkar, Tarun K.,Basak, Sankar,Ghosh, Sunil K.
, p. 759 - 762 (2000)
A short synthesis of methyl (SR)-8,10-dichloro- 1,2,3,4,5,6-hexahydro-6- hydroxy-1-methyl-1,9-phenanthroline-6-carboxylate (14) has been achieved en route to conformationally restricted analogues of nicotine and anabasine. The key feature of this process involves an efficient intramolecular Hamaguchi- Ibata reaction of 11. (C) 2000 Elsevier Science Ltd.