26281-43-6

Basic information

• Product Name: 3,5-dichloro-2-hydroxybenzenesulphonic acid
• Synonyms: 3,5-dichloro-2-hydroxybenzenesulphonic acid;2-Hydroxy-3,5-dichlorobenzenesulfonic acid;54970-72-8 (Mono-hydrochloride salt);Einecs 247-582-4;2-Hydroxy-3,5-dichloro-benzenesulphonic acid
• CAS NO: 26281-43-6
• Molecular Formula: C₆H₄Cl₂O₄S
• Molecular Weight: 243.06456
• EINECS: 247-582-4
• Mol File: 26281-43-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.806g/cm³
• CAS DataBase Reference: 3,5-dichloro-2-hydroxybenzenesulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dichloro-2-hydroxybenzenesulphonic acid(26281-43-6)
• EPA Substance Registry System: 3,5-dichloro-2-hydroxybenzenesulphonic acid(26281-43-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 26281-43-6(Hazardous Substances Data)

Usage

General Description

3,5-dichloro-2-hydroxybenzenesulphonic acid, also known as DCHBSA, is a chemical compound containing two chlorine atoms, a hydroxyl group, and a sulfonic acid group attached to a benzene ring. It is used in the production of dyes and pigments, as well as in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. DCHBSA is a strong acid with high water solubility and is commonly used as a pH regulator and stabilizer in various industrial processes. It is important to handle DCHBSA with care, as it can cause skin and eye irritation and may be harmful if ingested or inhaled.

InChI:InChI=1/C6H4Cl2O4S.Na/c7-3-1-4(8)6(9)5(2-3)13(10,11)12;/h1-2,9H,(H,10,11,12);/q;+1/p-1

Upstream product

• 23378-88-3 3,5-dichloro-2-hydroxybenzenesulfonyl chloride 
• 88-06-2 2,4,6-Trichlorophenol 
• 125927-93-7 3,5-dichloro-2-hydroxybenzenesulfinic acid 
• 576-24-9 2,3-dichlorophenol 
• 553-82-2 1,3-dichloro-4-methoxybenzene 
• 120-83-2 2,4-dichlorophenol 

Downstream Products

• 609-89-2 2,4-dichloro-6-nitrophenol 

Relevant articles and documents

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Sulfonation and sulfation in the reactions of the chloro- and dichlorophenols, 3-fluorophenol and (2,3-, 2,4- and 3,4-dichlorophenoxy)acetic acid with concentrated aqueous sulfuric acid and sulfur trioxide

The chloro- and dichlorophenols have been sulfonated with sulfuric acid and with SO3 in aprotic solvents.In the sulfonations with concentrated aqueous sulfuric acid, the sulfonic acid isomer distribution is determined mainly by the ortho- and para-directing and activating effect of the hydroxy substituent; this is also the determining factor in the aprotic sulfonations using up to 1.0 equiv of SO3.Upon using larger amounts of SO3, the sulfonation isomer distribution is increasingly determined by additional sulfonation of the corresponding phenyl hydrogen sulfate, of which the -OSO3H substituent is deactivating and mainly para- (and further ortho-) directing.The sulfuric acid sulfonation of (2,3-, 2,4- and 3,4-dichlorophenoxy)acetic acid leads to the exclusive formation of the 4-, 6- and 6-sulfonic acid, respectively.

Communications from the Laboratory of the London Institution. On the action of potassic sulphite on the haloid derivatives of phenol

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