26281-69-6 Usage
Originator
Droctil,Ciba Geigy,Italy,1971
Manufacturing Process
p-Hydroxy-benzoic acid methyl ester was subjected to a condensation reaction
with 3-hexoxy-2-hydroxy-1-chloropropane in the presence of sodium ethylate
and ethanol as a solvent, yielding p-(3-hexoxy-2-hydroxy)-propoxy-benzoic
acid methyl ester.62 g of this intermediate product were admixed with 250 cc of 2N sodium
hydroxide and the resulting mixture was refluxed for three hours. The reaction
mixture was allowed to cool and was made acid with concentrated
hydrochloric acid while cooling it on ice. An oil separated out which was
extracted with ether. The ether extract solution was dried over sodium sulfate
and then the ether was distilled off, leaving a crystalline mass as a residue.
The crystalline product was recrystallized from a mixture of benzene and
petroleum ether, yielding a compound having a MP of 68°C.
Therapeutic Function
Choleretic
Check Digit Verification of cas no
The CAS Registry Mumber 26281-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,2,8 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26281-69:
(7*2)+(6*6)+(5*2)+(4*8)+(3*1)+(2*6)+(1*9)=116
116 % 10 = 6
So 26281-69-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H24O5/c1-2-3-4-7-10-20-11-13(17)12-21-15-9-6-5-8-14(15)16(18)19/h5-6,8-9,13,17H,2-4,7,10-12H2,1H3,(H,18,19)
