262852-01-7

Usage

Uses

Used in Pharmaceutical Industry:
(3-fluorobicyclo[1.1.1]pentane-1-yl)methanol is used as a building block for the synthesis of various pharmaceuticals, leveraging its unique properties and stability to create bioactive molecules with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (3-fluorobicyclo[1.1.1]pentane-1-yl)methanol serves as a key component in the development of new drugs, taking advantage of its fluorine atom and bicyclic structure to enhance the compound's reactivity and potential for diverse chemical interactions.
Used in Organic Synthesis:
(3-fluorobicyclo[1.1.1]pentane-1-yl)methanol is utilized as an intermediate in organic synthesis, where its unique properties and structural features contribute to the creation of a wide range of chemical compounds for various applications.

Upstream product

• 56842-95-6 bicyclo<1.1.1>pentane-1,3-dicarboxylic acid 
• 115913-30-9 1,1′-(bicyclo[1.1.1]pentane-1,3-diyl)bis(ethan-1-one) 
• 146038-53-1 3-fluorobicyclo<1.1.1>pentane-1-carboxylic acid 

Relevant academic research and scientific papers

Large-Scale Synthesis and Modifications of Bicyclo[1.1.1]pentane-1,3-dicarboxylic Acid (BCP)

In flow photochemical addition of propellane to diacetyl allowed construction of the bicyclo[1.1.1]pentane (BCP) core in a 1 kg scale within 1 day. Haloform reaction of the formed diketone in batch afforded bicyclo[1.1.1]pentane-1,3-dicarboxylic acid in a

3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of formula (I') and pharmaceutical compositions and their use in reducing Widely Interspaced Zinc Finger Motifs (WIZ) expression levels, or inducing fetal hemoglobin (HbF) expression, and in the treatment of inherited blood disorders (e.g., hemoglobinopathies, e.g., beta-hemoglobinopathies), such as sickle cell disease and beta-thalassemia.

3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure provides a compound of Formula (I′): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.

Propeller alkane derivative, and preparation method, pharmaceutical composition and application thereof

The invention provides a compound as shown in a general formula (I), a preparation method thereof, a pharmaceutical composition containing the compound and application of the compound as an AT2R regulator, wherein R1 is defined in the specification, and t

N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF

A compound of Formula (I) is provided that has been shown to be useful for treating a disease caused by a viral infection: (I) wherein R1, R2, R3, A, L, m, n, p and q are as defined herein.