262852-70-0Relevant articles and documents
Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase
-
Page/Page column 30; 31, (2018/02/28)
The present disclosure relates to the synthesis of non-natural analogs of S-adenosyl-L-methionine (SAM) and/or of Se-adenosyl-L-methionine (SeAM) by reacting a methionine analog and adenosine triphosphate (ATP) in the presence of at least one methionine adenosyltransferase (MAT), and to use thereof with downstream SAM and/or SeAM utilizing enzymes. The non-natural analogs of SAM and/or SeAM have the general formula: where X is S or Se, and R1 is an alkyl group.
Synthesis and application in peptide chemistry of amino acids possessing an optically active selenohomocysteine skeleton.
Pande,Rudick,Walter
, p. 1440 - 1445 (2007/10/06)
-