26296-35-5

Usage

Uses

Used in Pharmaceutical Industry:
(1R,8aα)-Decahydro-5β-[(E)-5-hydroxy-3-methyl-3-pentenyl]-1,4aβ-dimethyl-6-methylene-1α-naphthalenemethanol is used as a pharmaceutical compound for its potential antimicrobial and antifungal properties. Its complex structure and biological activities make it a promising candidate for the development of new drugs and treatments.
Used in Chemical Industry:
(1R,8aα)-Decahydro-5β-[(E)-5-hydroxy-3-methyl-3-pentenyl]-1,4aβ-dimethyl-6-methylene-1α-naphthalenemethanol is used as a chemical intermediate in the synthesis of various compounds due to its complex structure and functional groups. Its unique properties can be utilized in the development of new chemical products and materials.

Upstream product

• 640-28-8 agathic acid 
• 640-28-8 labda-8⁽¹⁷⁾,13-diene-15,19-dioic acid 
• 1757-85-3 dimethyl agathate 
• 14027-05-5 agathic acid 15-methyl ester 
• 66471-91-8 Villenatriol-15,19-diacetat 
• 69308-72-1 isocupressic acid 
• 1909-96-2 methyl (E)-15-acetoxylabda-8⁽¹⁷⁾,13-dien-19-oate 
• 66471-92-9 Acetic acid (1S,4aS,5R,8aR)-5-((E)-5-acetoxy-3-methyl-pent-3-enyl)-1,4a-dimethyl-6-methylene-7-oxo-decahydro-naphthalen-1-ylmethyl ester 
• 3954-67-4 isocupressic acid methyl ester 
• 90374-84-8 dimethyl ester of 15-O-succinylisocupressic acid 
• 90527-77-8 methyl 18-acetoxyanticopulate 
• 86341-42-6 dimethyl 19-O-succinylagatholate 

Downstream Products

• 66471-77-0 villenol 

Relevant academic research and scientific papers

Agathadiol, a labdane diterpenoid from juniper berries, is a positive allosteric modulator of CB1R

The neutral fraction of a juniper (Juniperus communis L.) berries acetone extract could positively modulate the activity of type 1 - cannabinoid receptor (CB1R). Bioactivity-directed fractionation identified the labdane diterpenoid agathadiol (4) as a positive allosteric modulator of CB1R, while closely related analogues were inactive. Agathadiol (4) is a minor constituent of juniper, but could be more conveniently obtained by semisynthesis from agathic acid (8), a major constituent of Manila copal.

ENT-LABDANE-TYPE DITERPENE GLUCOSIDES FROM LEAVES OF RUBUS CHINGII

Previuosly, a sweet steviol bisglucoside named rubusoside was isolated from leaves of a Chinese Rubus spp. which was tentatively assigned as R. chingii.From leaves of Japanese Rubus chingii (Japanese name Gosho-Ichigo) which are not sweet, five ent-labdane-type diterpene glucosides named goshonosides F1-5 were isolated instead of rubososide and their structures were elucidated.The name 'R. suavissimus' has been proposed for the Chinese plant.Key Word Index - Rubus chingii; Rubus suavissimus; Rosaceae; glucosides of ent-labdane type diterpenes; goshonosides F1-5.

DERIVATIVES OF ANTICOPALIC ACID AND OTHER NEW COMPOUNDS FROM THE OLEORESIN OF Pinus pumila

From the oleoresin of the Japanese stone pine the previously known agatholic, agathalic, agathic and 3β-hydroxyanticopalic acids, and also the new acids 19-methoxyanticopalic and 19-O-succinylagatholic acids have been isolated and identified in the form of their methyl esters.Two new esters of 1-borneol have been isolated and characterized in the form of their acetates - the ferulate and the p-coumarate.