263024-64-2Relevant academic research and scientific papers
Synthesis of heterofunctionalized multidentate diphosphines
Quirmbach, Michael,Holz, Jens,Tararov, Vitali I.,B?rner, Armin
, p. 775 - 780 (2007/10/03)
The synthesis of new chiral multidentate amino- and amidophosphine ligands bearing up to six potential coordination sites were synthesized starting from L-valine. Based on these compounds chiral Ru(II) complexes were prepared, characterized and tested in the asymmetric transfer hydrogenation of aryl-alkyl ketones. In all cases investigated the catalyst bearing additional hydroxy groups gave lower conversions than the complex without hydroxy groups. Highest enantioselectivity was achieved with isobutyrophenone as substrate (69%ee). (C) 2000 Elsevier Science Ltd.
